Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Contrasting linkage-disequilibrium patterns between cases and controls as a novel association-mapping method.

American journal of human genetics - 1 May 2006

Zaykin Dmitri V, Meng Zhaoling, Ehm Margaret G

Abstract excerpt

Identification and description of genetic variation underlying disease susceptibility, efficacy, and adverse reactions to drugs remains a difficult problem. One of the important steps in the analysis of variation in a candidate region is the characterization of linkage disequilibrium (LD). In a region of genetic association, the extent of LD varies between the case and the control groups. Separate plots of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chromosome Mapping
Share to Computational Biology
Share to Computer Simulation

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Cytochrome P-450 CYP2D6

Share to Genetic Markers

Share to Linkage Disequilibrium

Share to Models, Statistical

Share to Quantitative Trait, Heritable

Source

Open in PubMed Open full text

Identifiers

PMID: 16642430
DOI: 10.1086/503710
PMCID: PMC1474029

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Contrasting linkage-disequilibrium patterns between cases and controls as a novel association-mapping method.PMID 16642430Read ↗

Contrasting linkage disequilibrium as a multilocus family-based association test.Semantic proximity Read ↗

Genome-wide comparisons of variation in linkage disequilibrium.Semantic proximity Read ↗

Improving power in contrasting linkage-disequilibrium patterns between cases and controls.Semantic proximity Read ↗

The optimal measure of linkage disequilibrium reduces error in association mapping of affection status.Semantic proximity Read ↗

Estimating Disequilibrium Coefficients.Semantic proximity Read ↗

Estimating disequilibrium coefficients.Semantic proximity Read ↗

Linkage disequilibrium and association mapping.Semantic proximity Read ↗

Phase uncertainty in case-control association studies.Semantic proximity Read ↗

Statistical analysis for haplotype-based matched case-control studies.Semantic proximity Read ↗

Combining the transmission disequilibrium test and case-control methodology using generalized logistic regression.Semantic proximity Read ↗

Linkage Disequilibrium Statistics and Block Visualization.Semantic proximity Read ↗

Tests of trait-haplotype association when linkage phase is ambiguous, appropriate for matched case-control and cohort studies with competing risks.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.