Article
Combining the transmission disequilibrium test and case-control methodology using generalized logistic regression.
European journal of human genetics : EJHG - 1 Nov 2004
Nagelkerke Nico J D, Hoebee Barbara, Teunis Peter, Kimman Tjeerd G
Abstract excerpt
To study the role of genetic factors in the etiology, susceptibility, or severity of disease, several methods are available. In a transmission disequilibrium test, genotypes of cases are compared to those of their parents to explore whether a specific allele, or marker, at a locus of interest app...
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