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Article

Combining the transmission disequilibrium test and case-control methodology using generalized logistic regression.

European journal of human genetics : EJHG - 1 Nov 2004

Nagelkerke Nico J D, Hoebee Barbara, Teunis Peter, Kimman Tjeerd G

Abstract excerpt

To study the role of genetic factors in the etiology, susceptibility, or severity of disease, several methods are available. In a transmission disequilibrium test, genotypes of cases are compared to those of their parents to explore whether a specific allele, or marker, at a locus of interest appears to be transmitted in excess of what is expected on the basis of Mendelian inheritance. Such apparent excess...

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PMID: 15340361
DOI: 10.1038/sj.ejhg.5201255

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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