Article
Genome-wide comparisons of variation in linkage disequilibrium.
Genome research - 1 Oct 2009
Teo Yik Y, Fry Andrew E, Bhattacharya Kanishka, Small Kerrin S, Kwiatkowski Dominic P, Clark Taane G
Abstract excerpt
Current genome-wide surveys of common diseases and complex traits fundamentally aim to detect indirect associations where the single nucleotide polymorphisms (SNPs) carrying the association signals are not biologically active but are in linkage disequilibrium (LD) with some unknown functional polymorphisms. Reproducing any novel discoveries from these genome-wide scans in independent studies is now a prerequisite...
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