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Article

Improving power in contrasting linkage-disequilibrium patterns between cases and controls.

American journal of human genetics - 1 May 2007

Wang Tao, Zhu Xiaofeng, Elston Robert C

Abstract excerpt

Genetic association studies offer an opportunity to find genetic variants underlying complex human diseases. The success of this approach depends on the linkage disequilibrium (LD) between markers and the disease variant(s) in a local region of the genome. Because, in the region with a disease mutation, the LD pattern among markers may differ between cases and controls, in some scenarios, it is useful to compare...

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Identifiers

PMID: 17436245
DOI: 10.1086/516794
PMCID: PMC1852728

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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