Article
Phase uncertainty in case-control association studies.
Genetic epidemiology - 1 Sept 2009
Won Sungho, Kim Sulgi, Elston Robert C
Abstract excerpt
The possible evidence for association comprises three types of information: differences between cases and controls in allele frequencies, in parameters for Hardy-Weinberg disequilibrium (HWD), and in parameters for linkage disequilibrium (LD). LD between marker and disease alleles results in a difference in at least one of the three types of parameters [Won and Elston, 2008]. However, the parameters for LD...
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