Article
Contrasting linkage disequilibrium as a multilocus family-based association test.
Genetic epidemiology - 1 Sept 2011
Yu Zhaoxia, Wang Shuang
Abstract excerpt
Linkage disequilibrium (LD) of genetic loci is routinely estimated and graphically illustrated in genetic association studies. It has been suggested that the information in LD is also useful for association mapping and genetic association can be detected by comparing LD patterns between cases and controls. Here, we extend this idea to analyze case-parents data by comparing LD patterns between transmitted and...
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