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Article

Plasmodium falciparum infection dynamics and transmission potential following treatment with sulfadoxine-pyrimethamine.

The Journal of antimicrobial chemotherapy - 1 Jul 2006

Gatton Michelle L, Cheng Qin

Abstract excerpt

OBJECTIVES: To investigate the overall efficacy of sulfadoxine-pyrimethamine (SP) treatment and the corresponding transmission potential for patients infected with SP-resistant Plasmodium falciparum. METHODS: A mathematical model of the in-host dynamics of P. falciparum infections was used to simulate infections with parasites having different numbers of mutations in the dhfr and dhps genes and their responses to...

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Source

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Identifiers

PMID: 16641113
DOI: 10.1093/jac/dkl158
PMCID: PMC1592320

Genes

DHFR
DHPS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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