Article
Determinants of treatment response to sulfadoxine-pyrimethamine and subsequent transmission potential in falciparum malaria.
American journal of epidemiology - 1 Aug 2002
Méndez Fabián, Muñoz Alvaro, Carrasquilla Gabriel, Jurado Diana, Arévalo-Herrera Myriam, Cortese Joseph F, Plowe Christopher V
Abstract excerpt
Drug resistance is contributing to increasing mortality from malaria worldwide. For assessment of the role of resistance-conferring parasite mutations on treatment responses to sulfadoxine-pyrimethamine (SP) and transmission potential, 120 subjects with uncomplicated falciparum malaria from Buenaventura, Colombia, were treated with SP and followed for 21 days in the period February 1999 to May 2000. Exposures of...
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