Article
Evolution of resistance to sulfadoxine-pyrimethamine in Plasmodium falciparum.
Antimicrobial agents and chemotherapy - 1 Jun 2004
Gatton Michelle L, Martin Laura B, Cheng Qin
Abstract excerpt
The development of resistance to sulfadoxine-pyrimethamine by Plasmodium parasites is a major problem for the effective treatment of malaria, especially P. falciparum malaria. Although the molecular basis for parasite resistance is known, the factors promoting the development and transmission of these resistant parasites are less clear. This paper reports the results of a quantitative comparison of factors...
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