Article
BAT1, a putative anti-inflammatory gene, is associated with chronic Chagas cardiomyopathy.
The Journal of infectious diseases - 15 May 2006
Ramasawmy Rajendranath, Cunha-Neto Edecio, Faé Kellen C, Müller Natalie G, Cavalcanti Vanessa L, Drigo Sandra A, Ianni Barbara, Mady Charles, Kalil Jorge, Goldberg Anna Carla
Abstract excerpt
BACKGROUND: It is not understood why only a subset of individuals infected with Trypanosoma cruzi develop chronic Chagas cardiomyopathy (CCC). Patients with CCC display high levels of circulating proinflammatory cytokines. Heart-infiltrating lymphocytes from patients with CCC also express proinfl...
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