Immunogenetic risk and protective factors for the idiopathic inflammatory myopathies: distinct HLA-A, -B, -Cw, -DRB1, and -DQA1 allelic profiles distinguish European American patients with different myositis autoantibodies.

doi:10.1097/01.md.0000217525.82287.eb

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

Immunogenetic risk and protective factors for the idiopathic inflammatory myopathies: distinct HLA-A, -B, -Cw, -DRB1, and -DQA1 allelic profiles distinguish European American patients with different myositis autoantibodies.

Medicine - 1 Mar 2006

O'Hanlon Terrance P, Carrick Danielle Mercatante, Targoff Ira N, Arnett Frank C, Reveille John D, Carrington Mary, Gao Xiaojiang, Oddis Chester V, Morel Penelope A, Malley James D, Malley Karen, Shamim Ejaz A, Rider Lisa G, Chanock Stephen J, Foster Charles B, Bunch Thomas, Blackshear Perry J, Plotz Paul H, Love Lori A, Miller Frederick W

Abstract excerpt

The idiopathic inflammatory myopathies (IIM) are systemic connective tissue diseases defined by chronic muscle inflammation and weakness associated with autoimmunity. We have performed low to high resolution molecular typing to assess the genetic variability of major histocompatibility complex loci (HLA-A, -B, -Cw, -DRB1, and -DQA1) in a large population of European American patients with IIM (n = 571)...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Autoantibodies

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Autoimmune Diseases

Share to HLA-A Antigens

Share to HLA-B Antigens

Share to HLA-C Antigens

Share to HLA-DQ alpha-Chains

Share to HLA-DQ Antigens

Share to Myositis

Source

Open in PubMed

Identifiers

PMID: 16609350
DOI: 10.1097/01.md.0000217525.82287.eb

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Immunogenetic risk and protective factors for the idiopathic inflammatory myopathies: distinct HLA-A, -B, -Cw, -DRB1, and -DQA1 allelic profiles distinguish European American patients with different myositis autoantibodies.PMID 16609350Read ↗

Immunogenetic risk and protective factors for the idiopathic inflammatory myopathies: distinct HLA-A, -B, -Cw, -DRB1 and -DQA1 allelic profiles and motifs define clinicopathologic groups in caucasians.Semantic proximity Read ↗

Distinct HLA associations with autoantibody-defined subgroups in idiopathic inflammatory myopathies.Semantic proximity Read ↗

An update on the immunogenetics of idiopathic inflammatory myopathies: major histocompatibility complex and beyond.Semantic proximity Read ↗

Immunogenetics of Idiopathic Inflammatory Myopathies: The Role of HLA Genes Within and Beyond the Ancestral Haplotype.Semantic proximity Read ↗

Risk factors and disease mechanisms in myositis.Semantic proximity Read ↗

Genome-wide association study identifies HLA 8.1 ancestral haplotype alleles as major genetic risk factors for myositis phenotypes.Semantic proximity Read ↗

Focused HLA analysis in Caucasians with myositis identifies significant associations with autoantibody subgroups.Semantic proximity Read ↗

Dense genotyping of immune-related loci in idiopathic inflammatory myopathies confirms HLA alleles as the strongest genetic risk factor and suggests different genetic background for major clinical subgroups.Semantic proximity Read ↗

HLA polymorphisms in African Americans with idiopathic inflammatory myopathy: allelic profiles distinguish patients with different clinical phenotypes and myositis autoantibodies.Semantic proximity Read ↗

HLA variation analysis and autoantigen epitope prediction in idiopathic inflammatory myopathies.Semantic proximity Read ↗

Genetic risk and protective factors for idiopathic inflammatory myopathy in Koreans and American whites: a tale of two loci.Semantic proximity Read ↗

The Genetics of Autoimmune MyositisSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.