Article
HLA variation analysis and autoantigen epitope prediction in idiopathic inflammatory myopathies.
Rheumatology (Oxford, England) - 5 Mar 2026
Jassal Bandana, Chopra Gouri, Dhall Aishwarya, Kumar Mukesh, Bhadu Danveer, Kumar Uma, Vishnu Venugopalan Yamuna, Bhatia Rohit, Suri Vaishali, Deepak Rakesh Kumar, Sharma Mehar Chand
Abstract excerpt
OBJECTIVE: To identify HLA associations with clinical and autoantibody-defined subgroups of idiopathic inflammatory myopathy (IIM) and predict potential immunogenic epitopes presented by subgroup-specific HLA alleles. METHODS: An observational case-control study was conducted including 147 biopsy-confirmed IIM patients and 114 ethnically matched healthy controls. Patients were classified into clinical and...
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