Article
Risk factors and disease mechanisms in myositis.
Nature reviews. Rheumatology - 20 Apr 2018
Miller Frederick W, Lamb Janine A, Schmidt Jens, Nagaraju Kanneboyina
Abstract excerpt
Autoimmune diseases develop as a result of chronic inflammation owing to interactions between genes and the environment. However, the mechanisms by which autoimmune diseases evolve remain poorly understood. Newly discovered risk factors and pathogenic processes in the various idiopathic inflammatory myopathy (IIM) phenotypes (known collectively as myositis) have illuminated innovative approaches for understanding...
Topics
- Disease Management
- Environmental Exposure
- Genetic Heterogeneity
- Genetic Predisposition to Disease
- HLA Antigens
- Haplotypes
- Humans
- Myositis
- Phenotype