Article
p16(INK4alpha)/exon 2 mutations in squamous cell carcinoma of the head and neck region.
Acta oto-laryngologica - 1 Apr 2006
Lehnerdt G, Fischer M
Abstract excerpt
CONCLUSIONS: In the samples of squamous cell carcinoma (SCC) of the head and neck region studied, mutations of exon 2 were quite rare. In contrast to the other three mutations, the G to C transversion on position 169 (Ala57Pro) has been found in several other studies before. Further investigations on mutations of the other exons 1alpha, 1beta and 3 are necessary. OBJECTIVE: Alterations of p16(INK4A) have been...
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