Article
The correlation between p16 expression and INK4a locus mutation with grades and stages in oral squamous cell carcinoma.
Indian journal of pathology & microbiology - 1 Jan 2000
Sargolzaei Soudabeh, Farhadi Sareh, Kazemi Bahram, Bandehpour Mojgan, Kharazifard Mohammad Javad
Abstract excerpt
OBJECTIVE: p16INK4a is a tumor suppressor gene playing a critical role. Researches have indicated the gene to be altered in oral squamous cell carcinoma. Present studies have tried to assess the correlation between p16INK4a expression and INK4a locus mutation in relation to grades and stages of this tumor. MATERIALS AND METHODS: Expression of p16INK4a was studied immunohistochemically in 58 oral squamous sell...
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