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Article

p16/CDKN2 alterations and pRb expression in oesophageal squamous carcinoma.

Molecular pathology : MP - 1 Apr 1998

Busatto G, Shiao Y H, Parenti A R, Baffa R, Ruol A, Plebani M, Rugge M

Abstract excerpt

BACKGROUND: Upregulation of the cell cycle associated genes, p16/CDKN2 and the retinoblastoma susceptibility gene (Rb), is commonly seen during the proliferation of normal cells. An inverse relation between the expression of p16/CDKN2 and Rb has been noted in many tumours, but has not yet been determined in oesophageal squamous carcinoma. AIMS: To investigate p16/CDKN2 genetic alterations and both the p16/CDKN2...

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Identifiers

PMID: 9713590
DOI: 10.1136/mp.51.2.80
PMCID: PMC395614

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Source receipt: pubmed, retrieved 7 Sept 2026.

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