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Article

The nACHR4 594C/T polymorphism in Alzheimer disease.

Rejuvenation research - 1 Jan 2006

Vasto Sonya, Candore Giuseppina, Aquino Alessandra, Bulati Matteo, Balistreri Carmela Rita, Grimaldi Maria Paola, Ditta Vito, Colonna-Romano Giuseppina, Lio Domenico, Vitello Salvo, Barbieri Rainer, Caruso Calogero

Abstract excerpt

Alzheimer disease (AD) is the most common form of dementia with complex etiology and multifactorial origin. Although several neurochemical deficits have been described in AD patients, explanation of the nature of the cognitive disturbance is focused on the "cholinergic hypothesis." The neuronal nicotinic acetylcholine receptor (neuronal nAChR) belongs to the superfamily of ionic channel activated by ligand. This...

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PMID: 16608406
DOI: 10.1089/rej.2006.9.107

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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