Article
Association between a genetic variant of the alpha-7 nicotinic acetylcholine receptor subunit and four types of dementia.
Dementia and geriatric cognitive disorders - 1 Jan 2009
Fehér Agnes, Juhász Anna, Rimanóczy Agnes, Csibri Eva, Kálmán János, Janka Zoltán
Abstract excerpt
We tested the hypothesis whether the partially duplicated variant of alpha7 nicotinic acetylcholine receptor subunit gene (CHRFAM7A) 2-bp deletion (-2 bp) polymorphism and apolipoprotein E (ApoE) epsilon4 allele confer susceptibility to Alzheimer's disease (AD), dementia with Lewy bodies (DLB), Pick's disease (PiD) and vascular dementia (VD). The study included 175 AD, 35 DLB patients, 38 PiD, 96 VD and 175...
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