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Article

Phenotype analysis of mice deficient in the peptide transporter PEPT2 in response to alterations in dietary protein intake.

Pflugers Archiv : European journal of physiology - 1 Jun 2006

Frey Isabelle M, Rubio-Aliaga Isabel, Klempt Martina, Wolf Eckhard, Daniel Hannelore

Abstract excerpt

The peptide transporter PEPT2 mediates cellular uptake of di- and tripeptides driven by an inwardly directed electrochemical proton gradient. In mammals PEPT2 is found in a variety of organs such as kidney, lung, brain, enteric nervous system, and mammary gland. Highest expression levels are observed in renal proximal tubules where PEPT2 contributes to reabsorption of filtered di- and tripeptides. To assess the...

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PMID: 16586099
DOI: 10.1007/s00424-005-0042-5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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