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Article

How the intestinal peptide transporter PEPT-1 contributes to an obesity phenotype in Caenorhabditits elegans.

PloS one - 21 Jul 2009

Spanier Britta, Lasch Katrin, Marsch Silke, Benner Jacqueline, Liao Wenjuan, Hu Hao, Kienberger Hermine, Eisenreich Wolfgang, Daniel Hannelore

Abstract excerpt

BACKGROUND: Amino acid absorption in the form of di- and tripeptides is mediated by the intestinal proton-coupled peptide transporter PEPT-1 (formally OPT-2) in Caenorhabditits elegans. Transporter-deficient animals (pept-1(lg601)) show impaired growth, slowed postembryonal development and major changes in amino acid status. PRINCIPAL FINDINGS: Here we demonstrate that abolished intestinal peptide transport also...

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Identifiers

PMID: 19621081
DOI: 10.1371/journal.pone.0006279
PMCID: PMC2708923

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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