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Article

Targeted disruption of the peptide transporter Pept2 gene in mice defines its physiological role in the kidney.

Molecular and cellular biology - 1 May 2003

Rubio-Aliaga Isabel, Frey Isabelle, Boll Michael, Groneberg David A, Eichinger Hans M, Balling Rudi, Daniel Hannelore

Abstract excerpt

The peptide transporter PEPT2 mediates the cellular uptake of di- and tripeptides and selected drugs by proton-substrate cotransport across the plasma membrane. PEPT2 was functionally identified initially in the apical membrane of renal tubular cells but was later shown to be expressed in other tissues also. To investigate the physiological importance of PEPT2 and for a detailed analysis of the protein expression...

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Identifiers

PMID: 12697824
DOI: 10.1128/MCB.23.9.3247-3252.2003
PMCID: PMC153205

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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