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Article

Proton-coupled oligopeptide transporter family SLC15: physiological, pharmacological and pathological implications.

Molecular aspects of medicine - 1 Jan 2000

Smith David E, Clémençon Benjamin, Hediger Matthias A

Abstract excerpt

Mammalian members of the proton-coupled oligopeptide transporter family (SLC15) are integral membrane proteins that mediate the cellular uptake of di/tripeptides and peptide-like drugs. The driving force for uphill electrogenic symport is the chemical gradient and membrane potential which favors proton uptake into the cell along with the peptide/mimetic substrate. The peptide transporters are responsible for the...

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Identifiers

PMID: 23506874
DOI: 10.1016/j.mam.2012.11.003
PMCID: PMC3602806

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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