Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A new type of insertion mutation in monkey cells: insertion accompanied by long target site duplication.

Molecular & general genetics : MGG - 1 Oct 1991

Ohira M, Bae Y S, Ikeda H

Abstract excerpt

We have developed a system for the detection of a new type of insertion mutation in mammalian cells. We have used a shuttle vector, plasmid pNK1, which contains the SV40 and pBR322 replication origins, and ApR, galK, and neoR genes. This plasmid was introduced into monkey COS1 cells, allowed to replicate, and then recovered plasmids were reintroduced into Escherichia coli HB101 to detect insertion mutations in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Base Sequence
Share to Cell Line
Share to DNA

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Molecular Sequence Data

Share to Mutation

Share to Plasmids

Share to Restriction Mapping

Share to Transfection

Source

Identifiers

PMID: 1658594
DOI: 10.1007/BF00267452

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A new type of insertion mutation in monkey cells: insertion accompanied by long target site duplication.PMID 1658594Read ↗

A shuttle vector for analysis of illegitimate recombination in mammalian cells: effects of DNA topoisomerase inhibitors on deletion frequency.Semantic proximity Read ↗

Human l1 retrotransposition is associated with genetic instability in vivo.Semantic proximity Read ↗

Introduction of specific point mutations into RNA polymerase II by gene targeting in mouse embryonic stem cells: evidence for a DNA mismatch repair mechanism.Semantic proximity Read ↗

SV40-based shuttle viruses.Semantic proximity Read ↗

Homologous and Nonhomologous Recombination Resulting in Deletion: Effects of p53 Status, Microhomology, and Repetitive DNA Length and OrientationSemantic proximity Read ↗

Spontaneous mutations at aprt locus in a mammalian cell line defective in mismatch recognition.Semantic proximity Read ↗

Relative rates of insertion and deletion mutations in a microsatellite sequence in cultured cells.Semantic proximity Read ↗

Recombination between irradiated shuttle vector DNA and chromosomal DNA in African green monkey kidney cells.Semantic proximity Read ↗

Identification and characterization of a novel conserved DNA repeat.Semantic proximity Read ↗

Design of a selectable reporter for the detection of mutations in mammalian simple repeat sequences.Semantic proximity Read ↗

DNA sequence analysis of gamma radiation-induced deletions and insertions at the APRT locus of hamster cells.Semantic proximity Read ↗

Analysis of sequence specificity of 5-bromodeoxyuridine-induced reversion in cells containing multiple copies of a mutant gpt gene.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.