Article
SV40-based shuttle viruses.
Mutation research - 1 Jan 2000
Menck C F, Madzak C, Renault G, Margot A, Sarasin A
Abstract excerpt
We summarize in this paper the advantages of the shuttle virus system. These SV40-based vectors exhibit the unique properties of being packaged as SV40 pseudo-virions and of being able to infect host cells. Using these transient vectors, we show that their replication can be regulated in some monkey cell lines, in such a way that either low or very high amounts of plasmid DNA can be obtained. The stability of...
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