Article
Recombination between irradiated shuttle vector DNA and chromosomal DNA in African green monkey kidney cells.
Molecular and cellular biology - 1 Jan 1990
Mudgett J S, Taylor W D
Abstract excerpt
An autonomously replicating shuttle vector was used to investigate enhancement of plasmid-chromosome recombination in mammalian host cells by gamma irradiation and UV light. Sequences homologous to the shuttle vector were stably inserted into the genome of African green monkey kidney cells to act as the target substrate for these recombination events. The shuttle vector molecules were irradiated at various doses...
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