Recombination between irradiated shuttle vector DNA and chromosomal DNA in African green monkey kidney cells.

doi:10.1128/mcb.10.1.37-46.1990

Back to search

Article

Recombination between irradiated shuttle vector DNA and chromosomal DNA in African green monkey kidney cells.

Molecular and cellular biology - 1 Jan 1990

Mudgett J S, Taylor W D

Abstract excerpt

An autonomously replicating shuttle vector was used to investigate enhancement of plasmid-chromosome recombination in mammalian host cells by gamma irradiation and UV light. Sequences homologous to the shuttle vector were stably inserted into the genome of African green monkey kidney cells to act...

Topics

Animals
Blotting, Southern
Cell Line
Chlorocebus aethiops
DNA Damage
Dose-Response Relationship, Drug
Gamma Rays
Genetic Vectors
Mutation
Plasmids
Recombination, Genetic
Time Factors
Transfection
Ultraviolet Rays

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.