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Article

ET-1 Lys198Asn and ET(A) receptor H323H polymorphisms in heart failure. A case-control study.

Cardiology - 1 Jan 2006

Colombo Maria Giovanna, Ciofini Enrica, Paradossi Umberto, Bevilacqua Stefano, Biagini Andrea

Abstract excerpt

BACKGROUND: The endothelin (ET) system plays a central role in the control of myocardial function and its pathophysiology. The aim of the present study was to explore whether genetic variations of ET-1 (G/T substitution that predicts an Lys/Asn change at codon 198) and its receptor ET(A) (T/C in exon 6, H323H) could predispose carriers to heart failure (HF). METHODS: Genotyping at these two loci was done in 122...

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PMID: 16582543
DOI: 10.1159/000092374

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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