Article
Haplotype-based association analysis of 56 functional candidate genes in the IBD6 locus on chromosome 19.
European journal of human genetics : EJHG - 1 Jun 2006
Tello-Ruiz Marcela Karey, Curley Christine, DelMonte Terrye, Giallourakis Cosmas, Kirby Andrew, Miller Kathryn, Wild Gary, Cohen Albert, Langelier Diane, Latiano Anna, Wedemeyer Neils, Lander Eric, Schreiber Stefan, Annese Vito, Daly Mark J, Rioux John D
Abstract excerpt
Evidence from four independent linkage studies and two meta-analyses of genome-wide data support the existence of a locus conferring susceptibility to inflammatory bowel diseases (IBD) in chromosomal region 19p. Identification of a susceptibility allele in this approximately 28.5 Mb region with over 600 genes is a formidable task. To tackle this problem, we undertook two approaches: (1) haplotype-based...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
