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Article

Immunogenetic biomarkers in inflammatory bowel diseases: role of the IBD3 region.

World journal of gastroenterology - 7 Nov 2014

Muro Manuel, López-Hernández Ruth, Mrowiec Anna

Abstract excerpt

Many studies have demonstrated the linkage between the IBD3 region (6p21.1-23), an area which encompasses the famous human leukocyte antigen (HLA) complex, and Crohn's disease (CD) or ulcerative colitis (UC). IBD3 is the only region that meets genome-wide significance, and provides stronger evidence of the linkage than 16p13.1-16q12.2 (IBD1), the locus that contains the susceptibility gene CARD15. However,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Histocompatibility Antigens Class I

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Source

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Identifiers

PMID: 25386052
DOI: 10.3748/wjg.v20.i41.15037
PMCID: PMC4223237

Genes

TNF
MICA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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