Allelic exclusion of a T cell receptor-beta minilocus.

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Article

Allelic exclusion of a T cell receptor-beta minilocus.

Journal of immunology (Baltimore, Md. : 1950) - 1 Nov 1991

van Meerwijk J P, Iglesias A, Hansen-Hagge T, Bluethmann H, Steinmetz M

Abstract excerpt

A TCR-beta minilocus in germline configuration (beta M) has previously been shown to undergo rearrangement and expression in transgenic mice. To study allelic exclusion of TCR miniloci, several beta M transgenic mouse lines were generated and crossed with mice transgenic for a functionally rearra...

Topics

Alleles
Animals
Base Sequence
Gene Rearrangement, beta-Chain T-Cell Antigen Receptor
Genes
Mice
Mice, Transgenic
Molecular Sequence Data
Oligonucleotides
Polymerase Chain Reaction
Receptors, Antigen, T-Cell, alpha-beta
T-Lymphocytes
Thymus Gland

Source

Open in PubMed

Identifiers

PMID: 1655909

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-1655909-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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