Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Patterns of β-cell autoantibody appearance and genetic associations during the first years of life.

Diabetes - 1 Oct 2013

Ilonen Jorma, Hammais Anna, Laine Antti-Pekka, Lempainen Johanna, Vaarala Outi, Veijola Riitta, Simell Olli, Knip Mikael

Abstract excerpt

We analyzed demographic and genetic differences between children with various diabetes-associated autoantibodies reflecting the autoimmune process. In a prospective birth cohort comprising children with HLA-conferred susceptibility to type 1 diabetes (T1D), the pattern of autoantibody appearance was analyzed in 520 children with advanced β-cell autoimmunity associated with high risk for disease. In 315 cases, a...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Autoantibodies
Share to Autoimmunity

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Diabetes Mellitus, Type 1

Share to Finland

Share to Follow-Up Studies

Share to Gene Expression Regulation, Developmental

Share to Insulin Antibodies

Share to Islets of Langerhans

Source

Open in PubMed Open full text

Identifiers

PMID: 23835325
DOI: 10.2337/db13-0300
PMCID: PMC3781470

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Patterns of β-cell autoantibody appearance and genetic associations during the first years of life.PMID 23835325Read ↗

The first signs of beta-cell autoimmunity appear in infancy in genetically susceptible children from the general population: the Finnish Type 1 Diabetes Prediction and Prevention Study.Semantic proximity Read ↗

Primary islet autoantibody at initial seroconversion and autoantibodies at diagnosis of type 1 diabetes as markers of disease heterogeneity.Semantic proximity Read ↗

Associations between deduced first islet specific autoantibody with sex, age at diagnosis and genetic risk factors in young children with type 1 diabetes.Semantic proximity Read ↗

Genetic risk determines the emergence of diabetes-associated autoantibodies in young children.Semantic proximity Read ↗

HLA-DR-DQ haplotypes and specificity of the initial autoantibody in islet specific autoimmunity.Semantic proximity Read ↗

Predictors of the Initiation of Islet Autoimmunity and Progression to Multiple Autoantibodies and Clinical Diabetes: The TEDDY Study.Semantic proximity Read ↗

Islet autoantibody phenotypes and incidence in children at increased risk for type 1 diabetes.Semantic proximity Read ↗

Early Autoantibody Responses in Prediabetes Are IgG1 Dominated and Suggest Antigen-Specific RegulationSemantic proximity Read ↗

Dynamics of Islet Autoantibodies During Prospective Follow-Up From Birth to Age 15 Years.Semantic proximity Read ↗

Autoimmune Diabetes From Childhood to Adulthood: The Role of Pancreatic Autoantibodies and HLA-DRB1 Genotype.Semantic proximity Read ↗

Data-Driven Phenotyping of Presymptomatic Type 1 Diabetes Using Longitudinal Autoantibody Profiles.Semantic proximity Read ↗

Age at development of type 1 diabetes- and celiac disease-associated antibodies and clinical disease in genetically susceptible children observed from birth.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.