Article
Young age and HLA markers enhance the risk of progression to type 1 diabetes in antibody-positive siblings of diabetic children.
Journal of autoimmunity - 1 Dec 1998
Yamamoto A M, Deschamps I, Garchon H J, Roussely H, Moreau N, Beaurain G, Robert J J, Bach J F
Abstract excerpt
The contribution of autoantibodies, HLA markers and age to long-term estimates of risk of type 1 diabetes were examined after a median of 11 years (range 7.5-14) during the follow-up in a cohort of 234 siblings (aged 2-29 years) of French children with recent-onset type 1 diabetes, of whom 12 (5....
Topics
- Adolescent
- Adult
- Aged
- Aging
- Autoantibodies
- Child
- Child, Preschool
- Diabetes Mellitus, Type 1
- Disease Progression
- Female
- Follow-Up Studies
- Glutamate Decarboxylase
- HLA Antigens
- Humans
- Insulin Antibodies
- Islets of Langerhans
- Male
- Middle Aged