Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Multiple epigenetic maintenance factors implicated by the loss of Mll2 in mouse development.

Development (Cambridge, England) - 1 Apr 2006

Glaser Stefan, Schaft Julia, Lubitz Sandra, Vintersten Kristina, van der Hoeven Frank, Tufteland Katharina R, Aasland Rein, Anastassiadis Konstantinos, Ang Siew-Lan, Stewart A Francis

Abstract excerpt

Epigenesis is the process whereby the daughters of a dividing cell retain a chromatin state determined before cell division. The best-studied cases involve the inheritance of heterochromatic chromosomal domains, and little is known about specific gene regulation by epigenetic mechanisms. Recent evidence shows that epigenesis pivots on methylation of nucleosomes at histone 3 lysines 4, 9 or 27. Bioinformatics...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Apoptosis
Share to Epigenesis, Genetic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Fetal Growth Retardation

Share to Gene Deletion

Share to Gene Expression Regulation, Developmental

Share to Genes, Lethal

Share to Histone-Lysine N-Methyltransferase

Share to Myeloid-Lymphoid Leukemia Protein

Source

Identifiers

PMID: 16540515
DOI: 10.1242/dev.02302

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Multiple epigenetic maintenance factors implicated by the loss of Mll2 in mouse development.PMID 16540515Read ↗

A genome-wide knock-out screen for actors of epigenetic silencing reveals new regulators of germline genes and 2-cell like cell stateSemantic proximity Read ↗

ZMYM2 is essential for methylation of germline genes and active transposons in embryonic developmentSemantic proximity Read ↗

Plasticity in Dnmt3L-dependent and -independent modes of de novo methylation in the developing mouse embryo.Semantic proximity Read ↗

Strategies for dissecting epigenetic mechanisms in the mouse.Semantic proximity Read ↗

Rescuing DNMT1 Fails to Fully Reverse the Molecular and Functional Repercussions of Its Loss in Mouse Embryonic Stem CellsSemantic proximity Read ↗

Epigenetic regulator function through mouse gastrulation.Semantic proximity Read ↗

MLL4 is required after implantation, whereas MLL3 becomes essential during late gestation.Semantic proximity Read ↗

Dnmt3b recruitment through E2F6 transcriptional repressor mediates germ-line gene silencing in murine somatic tissuesSemantic proximity Read ↗

Establishment and Maintenance of Genomic Methylation Patterns in Mouse Embryonic Stem Cells by Dnmt3a and Dnmt3bSemantic proximity Read ↗

Dnmt3b catalytic activity is critical for its tumour suppressor function in lymphomagenesis and is associated with c-Met oncogenic signalling.Semantic proximity Read ↗

Mechanisms and function of de novo DNA methylation in placental development reveals an essential role for DNMT3BSemantic proximity Read ↗

Identification of distinct loci for de novo DNA methylation by DNMT3A and DNMT3B during mammalian development.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.