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Article

Strategies for dissecting epigenetic mechanisms in the mouse.

Nature genetics - 1 Nov 2005

Mager Jesse, Bartolomei Marisa S

Abstract excerpt

Epigenetics generally refers to heritable changes in gene expression that are independent of nucleotide sequence. With complete genome sequences in hand, understanding the epigenetic control of genomes is the next step towards comprehending how the same DNA sequence gives rise to different cells, lineages and organs. Epigenetics also contributes to individual variation in normal biology and in disease states. The...

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PMID: 16254566
DOI: 10.1038/ng1664

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