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Article

Multiple large surface photodynamic therapy sessions with topical methylaminolaevulinate in PTCH heterozygous mice.

The British journal of dermatology - 1 Apr 2006

Caty V, Liu Y, Viau G, Bissonnette R

Abstract excerpt

BACKGROUND: Photodynamic therapy (PDT) combines the administration of a photosensitizer with its subsequent activation by light of the appropriate wavelength. Methylaminolaevulinate (MAL) is a photosensitizer precursor, transformed by cells into protoporphyrin IX. The PTCH gene plays a central role in the genesis of basal cell carcinoma (BCC). The PTCH transgenic mouse develops microscopic BCCs when chronically...

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Share to Aminolevulinic Acid
Share to Carcinoma, Basal Cell
Share to Neoplasms, Radiation-Induced

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 16536820
DOI: 10.1111/j.1365-2133.2005.07056.x

Genes

MAL

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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