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Article

Structure and biological importance of the Spn1-Spt6 interaction, and its regulatory role in nucleosome binding.

Molecular cell - 10 Dec 2010

McDonald Seth M, Close Devin, Xin Hua, Formosa Tim, Hill Christopher P

Abstract excerpt

Eukaryotic transcription and mRNA processing depend upon the coordinated interactions of many proteins, including Spn1 and Spt6, which are conserved across eukaryotes, are essential for viability, and associate with each other in some of their biologically important contexts. Here we report cryst...

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Identifiers

PMID: 21094070
DOI: 10.1016/j.molcel.2010.11.014
PMCID: PMC3017428

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-21094070-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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