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Article

YtkD and MutT protect vegetative cells but not spores of Bacillus subtilis from oxidative stress.

Journal of bacteriology - 1 Mar 2006

Castellanos-Juárez Francisco X, Alvarez-Alvarez Carlos, Yasbin Ronald E, Setlow Barbara, Setlow Peter, Pedraza-Reyes Mario

Abstract excerpt

ytkD and mutT of Bacillus subtilis encode potential 8-oxo-dGTPases that can prevent the mutagenic effects of 8-oxo-dGTP. Loss of YtkD but not of MutT increased the spontaneous mutation frequency of growing cells. However, cells lacking both YtkD and MutT had a higher spontaneous mutation frequency than cells lacking YtkD. Loss of either YtkD or MutT sensitized growing cells to hydrogen peroxide (H2O2) and...

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Identifiers

PMID: 16513759
DOI: 10.1128/JB.188.6.2285-2289.2006
PMCID: PMC1428130

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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