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Article

Identification of multiple actin-binding sites in cofilin-phosphatase Slingshot-1L.

FEBS letters - 20 Mar 2006

Yamamoto Masahiro, Nagata-Ohashi Kyoko, Ohta Yusaku, Ohashi Kazumasa, Mizuno Kensaku

Abstract excerpt

Slingshot-1L (SSH1L) is a phosphatase that specifically dephosphorylates and activates cofilin, an actin-severing and -depolymerizing protein. SSH1L binds to and is activated by F-actin in vitro, and co-localizes with F-actin in cultured cells. We examined the F-actin-binding activity, F-actin-mediated phosphatase activation, and subcellular distribution of various mutants of SSH1L. We identified three sites...

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Identifiers

PMID: 16513117
DOI: 10.1016/j.febslet.2006.02.034

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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