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Article

Four and a half LIM protein 1 binds myosin-binding protein C and regulates myosin filament formation and sarcomere assembly.

The Journal of biological chemistry - 17 Mar 2006

McGrath Meagan J, Cottle Denny L, Nguyen Mai-Anh, Dyson Jennifer M, Coghill Imogen D, Robinson Paul A, Holdsworth Melissa, Cowling Belinda S, Hardeman Edna C, Mitchell Christina A, Brown Susan

Abstract excerpt

Four and a half LIM protein 1 (FHL1/SLIM1) is highly expressed in skeletal and cardiac muscle; however, the function of FHL1 remains unknown. Yeast two-hybrid screening identified slow type skeletal myosin-binding protein C as an FHL1 binding partner. Myosin-binding protein C is the major myosin-associated protein in striated muscle that enhances the lateral association and stabilization of myosin thick filaments...

Read the complete abstract on PubMed

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 16407297
DOI: 10.1074/jbc.M512552200

Genes

FHL1
FHL2
FHL3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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