Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

SALS, a WH2-domain-containing protein, promotes sarcomeric actin filament elongation from pointed ends during Drosophila muscle growth.

Developmental cell - 1 Dec 2007

Bai Jianwu, Hartwig John H, Perrimon Norbert

Abstract excerpt

Organization of actin filaments into a well-organized sarcomere structure is critical for muscle development and function. However, it is not completely understood how sarcomeric actin/thin filaments attain their stereotyped lengths. In an RNAi screen in Drosophila primary muscle cells, we identified a gene, sarcomere length short (sals), which encodes an actin-binding, WH2 domain-containing protein, required for...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Actin Cytoskeleton
Share to Animals, Genetically Modified

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Drosophila

Share to Fluorescent Antibody Technique

Share to Microfilament Proteins

Share to Myofibrils

Share to RNA, Small Interfering

Share to Sarcomeres

Source

Identifiers

PMID: 18061565
DOI: 10.1016/j.devcel.2007.10.003

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

SALS, a WH2-domain-containing protein, promotes sarcomeric actin filament elongation from pointed ends during Drosophila muscle growth.PMID 18061565Read ↗

The Hippo pathway controls myofibril assembly and muscle fiber growth by regulating sarcomeric gene expressionSemantic proximity Read ↗

The Whsc2/NelfA -dependent transcription complex is required for postnatal cardiac development and heart functionSemantic proximity Read ↗

Leiomodin 2 functions as a processive pointed-end elongator of actin filamentsSemantic proximity Read ↗

The nebulin repeat protein Lasp regulates I-band architecture and filament spacing in myofibrilsSemantic proximity Read ↗

Leiomodin 2 is a processive pointed-end elongator of actin filaments.Semantic proximity Read ↗

Bruno 1 regulates cytoskeleton dynamics and a temporal splicing transition to promote myofibril assembly, growth and maturation in <i>Drosophila</i> flight muscleSemantic proximity Read ↗

The short toes mutation of the axolotl.Semantic proximity Read ↗

Assembly and Maintenance of Sarcomere Thin Filaments and Associated Diseases.Semantic proximity Read ↗

Bruno 1/CELF regulates splicing and cytoskeleton dynamics to ensure correct sarcomere assembly in Drosophila flight musclesSemantic proximity Read ↗

The spectraplakin Short stop is an essential microtubule regulator involved in epithelial closure in Drosophila.Semantic proximity Read ↗

A Candidate RNAi Screen Reveals Diverse RNA-Binding Protein Phenotypes in Drosophila Flight MuscleSemantic proximity Read ↗

Nervous wreck, an SH3 adaptor protein that interacts with Wsp, regulates synaptic growth in Drosophila.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.