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Article

DNA repair XRCC1 Arg399Gln polymorphism is associated with the risk of development of end-stage renal disease.

Molecular biology reports - 1 Jun 2012

Trabulus Sinan, Guven Gulgun S, Altiparmak Mehmet R, Batar Bahadir, Tun Ozlem, Yalin Ayse S, Tunckale Aydin, Guven Mehmet

Abstract excerpt

Patients with end-stage renal disease (ESRD) display enhanced genomic damage. DNA repair gene polymorphisms may affect DNA repair capacity and modulate susceptibility to ESRD. In this study, we aimed to determine the frequency of polymorphisms in two DNA repair enzyme genes, Xeroderma pigmentosum complementation group D (XPD) and X-ray cross-complementing group 1 (XRCC1), in patients with ESRD and to evaluate...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 22302399
DOI: 10.1007/s11033-012-1529-8

Genes

XRCC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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