Article
DNA repair genes XPD and XRCC1 polymorphisms and risk of end-stage renal disease in Egyptian population.
Renal failure - 1 Feb 2015
Radwan Wafaa M, Elbarbary Hany S, Alsheikh Nevein M
Abstract excerpt
DNA repair gene polymorphisms may affect DNA repair capacity and modulate susceptibility to end-stage renal disease (ESRD). We aimed to determine the association of polymorphisms in xeroderma pigmentosum complementation group D (XPD) and X-ray cross-complementing group 1 (XRCC1) with ESRD development. Polymorphisms in XPD codons 312 and 751 and XRCC1 codon 399 were genotyped in 98 patients undergoing hemodialysis...
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