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Article

Genetic polymorphisms in DNA base excision repair gene XRCC1 and the risk of squamous cell carcinoma of the head and neck.

Journal of experimental & clinical cancer research : CR - 13 Mar 2009

Kowalski Michal, Przybylowska Karolina, Rusin Pawel, Olszewski Jurek, Morawiec-Sztandera Alina, Bielecka-Kowalska Anna, Pietruszewska Wioletta, Mlynarski Wojciech, Janusz Szemraj, Majsterek Ireneusz

Abstract excerpt

BACKGROUND: The genes of base excision repair (BER) pathway have been extensively studied in the association with various human cancers. We performed a case-control study to test the association between two common single nucleotide polymorphisms (SNPs) of XRCC1 gene with human head and neck squamous cell carcinoma (HNSCC). METHODS: The genotype analysis of Arg194Trp and Arg399Gln gene polymorphisms for 92 HNSCC...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 19284666
DOI: 10.1186/1756-9966-28-37
PMCID: PMC2660298

Genes

XRCC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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