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Article

The role of XRCC6 T-991C functional polymorphism in renal cell carcinoma.

Anticancer research - 1 Sept 2012

Chang Wen-Shin, Ke Hung-Lung, Tsai Chia-Wen, Lien Chi-Shun, Liao Wen-Ling, Lin Hui-Hui, Lee Meng-Hsuan, Wu Hsi-Chin, Chang Chao-Hsiang, Chen Chi-Cheng, Lee Hong-Zin, Bau Da-Tian

Abstract excerpt

BACKGROUND: The DNA non-homologous end-joining repair gene XRCC6 (Ku70) plays a key role in both the DNA double-strand break (DSB) repair and cell cycle arrest. Defects in DSB repair capacity can lead to genomic instability. We hypothesized that a variant in the XRCC6 gene was associated with sus...

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Source

Identifiers

PMID: 22993329

Genes

XRCC6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22993329-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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