Article
Chromosome 11q13.3 variant modifies renal cell cancer risk in a Chinese population.
Mutagenesis - 1 May 2012
Cao Qiang, Qin Chao, Ju Xiaobing, Meng Xiaoxin, Wang Meilin, Zhu Jian, Li Pu, Chen Jiawei, Zhang Zhengdong, Yin Changjun
Abstract excerpt
A recent genome-wide association study of renal cell carcinoma (RCC) in European population has identified genetic variants in the regions of 2p21 (rs7579899), 11q13.3 (rs7105934) and 12q24.31 (rs4765623) conferred susceptibility to RCC. In our study, we assessed whether these polymorphisms are also associated with RCC risk in a Chinese population. We genotyped these polymorphisms using TaqMan method and assessed...
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