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Article

Reduced expression of the transporter associated with antigen processing 1 molecule in malignant glioma cells, and its restoration by interferon-gamma and -beta.

Journal of neurosurgery - 1 Feb 2006

Satoh Eiji, Mabuchi Tadashi, Satoh Hiroki, Asahara Takayuki, Nukui Hideaki, Naganuma Hirofumi

Abstract excerpt

OBJECT: It remains unclear whether malignant glioma cells can deliver tumor antigens efficiently to major histocompatibility complex (MHC) Class I molecules. To elucidate the mechanism of antigen presentation in malignant gliomas, the authors examined the expression of the transporter associated with antigen processing 1 (TAP1), which transports antigens to MHC Class I molecules, and low-molecular-mass...

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Source

Identifiers

PMID: 16509500
DOI: 10.3171/jns.2006.104.2.264

Genes

TAP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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