Article
Transporter associated with antigen processing 1 (TAP1) expression and prognostic analysis in breast, lung, liver, and ovarian cancer.
Journal of molecular medicine (Berlin, Germany) - 1 Sept 2021
Tabassum Anika, Samdani Md Nazmus, Dhali Tarak Chandra, Alam Rahat, Ahammad Foysal, Samad Abdus, Karpiński Tomasz M
Abstract excerpt
Transporter associated with antigen processing 1 (TAP1) is a transporter protein that represent tumor antigen in the MHC I or HLA complex. Any defect in the TAP1 gene resulting in inadequate tumor tracking. TAP1 influences multidrug resistance (MDR) in human cancer cell lines and hinders the treatment during chemotherapeutic. The association of TAP1 in cancer progression remains mostly unknown and further study...
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