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Article

Lack of HLA‐class I antigens in human neuroblastoma cells: analysis of its relationship to TAP and tapasin expression

1 Feb 2001

Abstract excerpt

We studied the constitutive and the interferon (IFN)-gamma-induced expression of HLA class I antigen heavy chain, beta2-microglobulin (beta2m), TAP-1, TAP-2 and tapasin in a panel of eleven neuroblastoma cell lines. Surface expression of HLA class I antigens was low in eight out of eight neuroblastoma cell lines bearing MYC-N amplification and/or 1p deletion, while two out of three neuroblastoma cell lines...

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PMID: 11260505
DOI: 10.1034/j.1399-0039.2001.057002110.x

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