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Transporter Associated with Antigen ProcessingProteins (TAP-1 and TAP-2) Gene Expressionof MHC-I Downregulated in Oral SquamousCarcinoma

11 Feb 2025

Abstract excerpt

BACKGROUND: TAP-1 and TAP-2 are crucial proteins for loading antigenic peptides after proteasome-mediated endogenous processing of the MHC-I (Major Histocompatibility Complex- I) pathway. Our study aimed to explore the Transporter Associated with Antigen Processing proteins (TAP-1 and TAP-2) in oral squamous cell carcinoma and premalignant oral lesions. METHODS: We recruited a total of 135 subjects from the...

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PMID: 39950478
DOI: 10.2174/0118715303344715241225184322

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