Article
Checkpoint functions are required for normal S-phase progression in Saccharomyces cerevisiae RCAF- and CAF-I-defective mutants.
Proceedings of the National Academy of Sciences of the United States of America - 7 Mar 2006
Kats Ellen S, Albuquerque Claudio P, Zhou Huilin, Kolodner Richard D
Abstract excerpt
The chromatin-assembly factor I (CAF-I) and the replication-coupling assembly factor (RCAF) complexes function in chromatin assembly during DNA replication and repair and play a role in the maintenance of genome stability. Here, we have investigated their role in checkpoints and S-phase progression. FACS analysis of mutants lacking Asf1 or Cac1 as well as various checkpoint proteins indicated that normal rates of...
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