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Article

The yeast histone chaperone chromatin assembly factor 1 protects against double-strand DNA-damaging agents.

Genetics - 1 Dec 2005

Linger Jeffrey, Tyler Jessica K

Abstract excerpt

The removal of histones from DNA and their subsequent replacement is likely to be necessary for all processes that require access to the DNA sequence in eukaryotic cells. The histone chaperone chromatin assembly factor 1 (CAF-1) mediates histone H3-H4 assembly during DNA replication and nucleotide excision repair in vitro. We have found that budding yeast deleted for the genes encoding CAF-1 are highly sensitive...

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Source

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Identifiers

PMID: 16143623
DOI: 10.1534/genetics.105.043000
PMCID: PMC1456080

Genes

PCNA

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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